Nasal bone hypoplasia in trisomy 21 at 15-22 weeks' gestation

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Nasal bone hypoplasia in trisomy 21 at 15-22 weeks' gestation.

OBJECTIVE To investigate the potential value of ultrasound examination of the fetal profile for present/hypoplastic fetal nasal bone at 15-22 weeks' gestation as a marker for trisomy 21. METHODS This was an observational ultrasound study in 1046 singleton pregnancies undergoing amniocentesis for fetal karyotyping at 15-22 (median, 17) weeks' gestation. Immediately before amniocentesis the fet...

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Nasal bone assessment in fetuses with trisomy 21 at 16-24 weeks of gestation by three-dimensional ultrasound.

OBJECTIVE This study aims to investigate the length and shape of the nasal bones in fetuses with trisomy 21 at 16-24 weeks' gestation. METHOD We acquired three-dimensional volumes of the fetal profile from 41 fetuses with trisomy 21. The multiplanar mode was used to measure nasal bone length in the exact midsagittal plane and in parasagittal and oblique views of the fetal face and to examine ...

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Femur and humerus length in trisomy 21 fetuses at 11-14 weeks of gestation.

OBJECTIVE To determine the value of measuring fetal femur and humerus length at 11-14 weeks of gestation in screening for chromosomal defects. METHODS Femur and humerus lengths were measured using transabdominal ultrasound in 1018 fetuses immediately before chorionic villus sampling for karyotyping at 11-14 weeks of gestation. In the group of chromosomally normal fetuses, regression analysis ...

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Frontomaxillary facial angle in trisomy 21 fetuses at 16-24 weeks of gestation.

OBJECTIVES To establish a normal range for the frontomaxillary facial (FMF) angle by three-dimensional (3D) ultrasound imaging and to examine the FMF angle in trisomy 21 fetuses at 16-24 weeks of gestation. METHODS We measured the FMF angle using 3D volumes of the fetal profile obtained with the transducer parallel to the long axis of the nose and at 45 degrees to the palate, which had been a...

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Prenasal thickness in trisomy-21 fetuses at 16-24 weeks of gestation.

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ژورنال

عنوان ژورنال: Ultrasound in Obstetrics and Gynecology

سال: 2002

ISSN: 0960-7692

DOI: 10.1002/uog.19